Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep37 | Adrenal cortex (to include Cushing's) | ECE2017

Visinin-Like Protein-1 in the regulation of aldosterone biosynthesis

Gomez-Sanchez Celso , Kuppusamy Maniselvan , Ishimwe Jeanne , Williams Tracy , Mulatero Paolo , Gomez-Sanchez Elise

Visinin-Like Protein-1 (Vsnl1) is a member of the EF-hand calcium sensor protein family that is expressed in the zona glomerulosa of the rat and human adrenal and upregulated in aldosterone-producing adenomas.We studied the expression pattern of Vsnl1 and co-localization with the CYP11B2 enzyme and the zona glomerulosa (ZG) marker Dlk1 (ZOG) using double and triple immunofluorescence in the adrenal of rats on a normal, high and low sodium diets. We also ...